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Laser assisted in-situ keratomileusis, or LASIK, is the most common refractive surgery and
is generally a safe and effective treatment for refractive problems. LASIK involves the use of a laser to permanently change
the shape of the cornea, the clear covering of the front of the eye. LASIK is a quick and often painless procedure, and for
the majority of patients, the surgery improves vision and reduces the need for corrective eyewear. However, LASIK is a surgical
procedure conducted on a delicate part of the eye, and it is crucial that potential candidates are well educated on the benefits
and risks of the procedure. Patients need to understand the importance of a thorough pre-LASIK screening by their physician
to obtain optimal results from the procedure.
In a LASIK procedure, the goal is to correct the patient’s vision to the point of not needing glasses or contact
lenses. A high percentage of patients achieve this goal; however, official statistics indicate that many are unhappy, and
10% to 20% regress post-operatively and require a second surgical procedure. In some cases the enhancements achieve target
refraction but in others the patient cannot be corrected to 20/40 vision. These failures are problems for the refractive surgeon
and are often highly publicized by advocacy and watchdog groups such as The Council for Refractive Surgery Quality
Assurance.
Currently, no surgeon can scientifically predict or guarantee outcomes; however, some problematic patients can be successfully
treated before surgery if they have had their tears analyzed prior to LASIK.
In June 2002, new patient guidelines were introduced by the Eye Surgery Education Council (ESEC) at the annual meeting
of the American Society of Cataract and Refractive Surgeons (ASCRS). These guidelines encourage patient-surgeon communication
and careful screening of candidates prior to refractive surgery. "These guidelines will help patients understand whether or
not LASIK is right for them, what they should expect from their doctor and, ultimately, what to expect from the procedure.
As with all surgeries, the decision to undergo laser eye surgery should not be taken lightly," said ESEC Chair Roger Steinert,
MD, Associate Clinical Professor of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Potential patients reading the guidelines are informed they may be an "ideal" LASIK candidate, "less than ideal", or are
not a candidate at all. Those with allergic conjunctivitis, dry eye syndrome or corneal scarring discover they are "less than
ideal" candidates; however, some learn that they may be able to reconsider LASIK at a later date. The document explains, however,
that realistic expectations are essential to patient satisfaction. It notes that while "the overwhelming majority" of patients
who have had LASIK surgery are satisfied with their results, patients should be aware of the risks and should make an informed
decision based on the facts. The guidelines walk patients through the pre-LASIK screening examination, explaining every aspect
of the comprehensive vision exam.
LASIK surgeons (primarily ophthalmologists) understand how tear profiling is able to provide the practitioner with diagnostic
as well as prognostic information that may help to minimize and, in some cases, prevent problems from occurring.
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Related Links
LASIK Risks Understated --- by Stephanie Armour and Julie Appleby
Patients are at risk because doctors fail to do thorough screenings. With no standardization of screening
procedures, some doctors aren't conducting enough tests on patients to determine risk of complications, critics say. "They're
doing the surgery on people who should not be patients," says Aaron Levine, a Washington lawyer. He estimates that there are
about 100 malpractice lawsuits involving laser eye surgery.

Tips For Pre-operative Evaluation: Avoiding Ocular Surface Problems
- - - Peter Rapoza, MD, Boston, MA
Successful LASIK surgery is highly correlated with the optimal selection of the surgical candidate and the appropriate
preoperative preparation of the eyes. Patients with ocular surface disorders are usually highly motivated to undergo refractive
surgery because of their difficulty in wearing contact lenses. Ocular surface disorders including aqueous tear deficiency...can
lead to an inaccurate preoperative assessment or significantly alter surgical results. Preoperative diagnosis and treatment
of these conditions will convert the patient into an appropriate LASIK candidate, reduce the potential for poor outcomes and
maximize patient satisfaction.
Tips For Pre-operative Evaluation of the Refractive Surgery Patient
--- Helen Wu, MD, Boston, MA
The preoperative evaluation of the potential refractive surgery patient is a critical step in ensuring the success of
the procedure. The evaluation consists of a history and physical examination, both of which are important in selecting the
proper procedure and providing appropriate preoperative counseling.
Patients with...moderate dry eyes may be better candidates for PRK than LASIK. Patients with severe dry
eyes are not good candidates for either procedure.
In summary, it is important to recognize factors in the history or physical examination preoperatively which
can predispose to potential complications intraoperatively or postoperatively. With careful planning and counseling, many
potentially significant complications can be avoided.

Ocular Allergic Disease, Dry Eye, and LASIK --- by Jodi Luchs, MD, FACS
South Shore Eye Care in Wantagh, New York, and Cornea Service at Long Island Jewish Medical Center in New Hyde Park,
New York. Assistant Professor of Ophthalmology and Visual Sciences at the Albert Einstein College of Medicine in New York
City.
Ocular allergies and dry eye syndromes are chronic ocular surface diseases that can share similar features such as ocular
surface inflammation and mediator release. Ophthalmologists have learned that both ocular allergies and dry eyes are inflammatory
conditions that may, in fact, interact with each other; the presence of one may affect the severity of the other. Dry eye
syndromes can worsen the symptoms of ocular allergies because the altered tear film in these patients allows more antigens
to enter the conjunctiva, thereby intensifying the allergic response.

Forestalling LASIK Complications Simplifies Management Strategies: Patient selection supercedes
techniques and technology --- Dawn Adams, Contributing Editor
Performing surgery can result in complications—and LASIK surgery is no exception to that rule.
No matter how cautious the refractive surgeon, some patients will develop postop conditions. In fact, some say complications
management is rapidly becoming a subspecialty of its own.
"Managing complications is the fastest growing aspect of my practice,” says Alan N.
Carlson, MD, Associate Professor of Ophthalmology, Duke University Medical Center, Durham, NC.
"Managing LASIK complications begins in the preoperative stage by ensuring the prospective patient
is a good candidate for LASIK. You have to manage at-risk patients, either by telling them that they’re not good candidates
for LASIK or by treating the condition preoperatively. You must evaluate prospective patients...and
make sure that they don’t have irregular corneas or wound healing problems," says Eric D. Donnenfeld, MD, partner,
Ophthalmic Consultants of Long Island, Rockville Centre, NY.
Tear Film Analysis --- The cornea gets nutrition from the tear film on the surface
and the...way the front of the cornea heals after laser surgery is dependent on how healthy the tear film is.
An important factor is lactoferrin. We feel it is important when there is any suspicion of dry eye
to have the tear film lactoferrin measured. If it is low, studies have shown that there is an increased chance of needing
a fine tune surgery.
Tear film lactoferrin is also helpful in healing of the cornea. So if we find the level low before refractive surgery
we will treat it and correct it so the level is normal before proceeding. This can help the healing process and lessen the
chance of a complication.
If our exam and studies show that the tear film is reduced then we need to consider enhancing the tear film. Punctal
plugs are a way of plugging the tear drainage system so that natural tears stay on the cornea longer.
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SolAurum, Inc. * 304 Gary Rd.
* Raleigh * NC * 27606
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